Scanvio Medical develops AI-powered software that enables standard ultrasound devices to detect endometriosis with expert-level precision, significantly reducing the typical diagnostic delay from up to 12 years to as little as 1–3 years. The solution offers real-time anatomical guidance and labeling, making non-invasive diagnosis broadly accessible. The founding team brings together leading AI and ultrasound researchers, clinical experts, and a seasoned MedTech entrepreneur.

School Rebound has developed the Dynamilis iPad application, designed to enhance children's handwriting skills. The app offers a comprehensive analysis of handwriting, identifying areas for improvement, and provides tailored activities developed in collaboration with over 40 handwriting specialists. These activities, presented as games, are intended to make learning engaging and effective, whether at home, with a therapist, or at school. Dynamilis offers subscription plans tailored for parents, therapists, and schools, with access to content available in multiple languages including French, Italian, German, and English.

Sentinus AG is a Swiss-based startup founded in November 2023 and headquartered in Cham. It develops smart camera systems powered by proprietary deep-learning models to monitor manual assembly operations in real time, enabling automated quality control, live documentation, feedback to operators and instructions for upcoming steps. The solution is designed for high-mix, low-volume production settings where manual assembly errors are costly. Sentinus AG secured seed funding of CHF 150 000 via the Venture Kick programme in 2024 to accelerate product development and market launch. The founding team includes Jonas Conrad (executive lead) and Felix Schnarrenberger (technical lead), both with strong backgrounds in machine learning and robotics from ETH Zurich.

Seprify, formerly Impossible Materials, offers plant-based formulation ingredients, providing a sustainable alternative to the carcinogenic titanium dioxide. Initially targeting the food, pharma, and cosmetic sectors, its cellulose white pigment is ideal for plant-based products and has expansion potential in paint, coatings, and inks. Seprify's process also promises significant CO2 emissions reduction at scale.

Shape Biopharmaceuticals is developing SHAPEnano particles, a novel platform that enables patients’ own immune systems to produce therapeutic antibodies in vivo. This approach offers major advantages over conventional antibody therapies, including significantly reduced dosing frequency, elimination of anti-drug antibody responses, and lower production costs. Targeting large, underserved markets with blockbuster potential, Shape combines deep expertise in immunobiology, chemistry, and computational design to create next-generation immunotherapies. The founding team brings extensive experience from biotech ventures to global pharmaceutical companies.

Sartiq develops an AI-driven solution that converts a single garment photo into high-quality, on-model images, enabling fashion brands and e-commerce platforms to digitalise and scale their product photography in a fast, flexible, and cost-efficient way. By generating multiple model variations for each item, the company helps customers better visualise fit across different body types. The team combines strong technical and creative capabilities, led by Luca Ambrosini in product and commercial execution, Felipe driving full-stack and machine-learning development, and Andrea shaping user experience and visual quality.

SoHHytec, an EPFL spin-off, is a provider of innovative energy solutions that develops, builds, and operates Gardens and Forests of its proprietary Arbs (Artificial Trees) while offering Hydrogen and power as a service. Utilizing a patented photo-electrochemical technology, SoHHytec's product, the "Arb," mimics the function of real trees. It exclusively uses sunlight and water as inputs to simultaneously produce hydrogen (fuel), oxygen, and power (electricity and heat) on the same site, efficiently using minimal ground or roof space. Their integrated system achieves high solar-to-fuel and solar-to-electricity conversion efficiencies, operates at exceptional power and current densities, and provides cost-effective fuel and power production.

SolidWatts is a technology startup founded in October 2022, headquartered in Pully, Switzerland. It focuses on developing high-efficiency electric heating solutions for industrial processes that currently rely on fossil fuels. Their innovative Solid State Power Amplifier technology offers unprecedented power and efficiency, aiming to revolutionize industrial heating by making it cleaner and more sustainable. The company operates in the cleantech, energy efficiency, and renewable energy sectors.

SPEQQLE SA develops RefFIT, software for analyzing spectroscopic data in material science. It helps industries like manufacturing, semiconductors, and photonics with product development, quality control, and sorting. By leveraging machine learning techniques, the platform provides a no-code, model-based solution that reduces calibration time, making spectroscopic analysis faster, more accurate, and accessible. This innovative software simplifies complex data analysis, enabling new applications in material science. Founded in May 2024, SPEQQLE focuses on high-tech sectors such as materials, AI, and SaaS.

Founded in 2023 as an EPFL spin-off and based in Renens, SUNAXER develops next-generation receivers for concentrated solar collectors to accelerate the transition to renewable industrial heat. With industrial heat responsible for 20% of global carbon emissions, SUNAXER addresses this challenge by providing high-performance receivers coated with an innovative selective absorber layer. Their patented, energy- and cost-efficient manufacturing process ensures superior durability and optical efficiency, positioning the company as the preferred supplier for solar process heat system manufacturers.

SurgeonsLab AG, founded in March 2021 and based in Bern, Switzerland, creates patient-specific surgical training models using real medical images. Their platforms, such as SurgTrain™ and CathTrain™, offer high-fidelity simulations for neurosurgery and interventional radiology. These models enhance surgical skills through realistic practice, pre-operative planning, and validation of medical devices, ultimately improving patient outcomes. SurgeonsLab emphasizes precision, safety, and personalized medicine in their innovative training solutions.

Tandem develops precision therapeutics that target the disease-associated extracellular matrix - a key but often overlooked contributor to therapeutic resistance and poor outcomes in fibrotic tumors and organ fibrosis. By leveraging evolutionarily optimized peptides, the company aims to decode matrix-disease biology and overcome drug delivery barriers, ultimately improving treatment safety and efficacy for patients suffering from fibrotic conditions.

Tethys Robotics AG, a 2018 ETH Zurich spin-off, develops advanced underwater drones for challenging aquatic environments. Their flagship product, Tethys ONE, operates as both an ROV and AUV, performing precise inspections and surveys in turbid waters, currents up to 3.5 knots, and depths of 300 meters. Serving industries like hydropower, offshore wind, and search and rescue, Tethys ONE enhances safety and efficiency by reducing reliance on divers. Headquartered in Zurich, the company launched Tethys ONE globally in 2024, supported by organizations such as Venture Kick and ETH Zurich.

Transcality AG is a Swiss startup that builds virtual traffic replicas to aid in sustainable urban planning. Utilizing big data, cloud computing, machine learning, and simulation, Transcality develops digital twins of transportation networks, offering faster, cost-effective, and efficient models. These solutions help public authorities and engineering firms optimize transportation planning, reduce emissions, and contribute to a more sustainable future. Founded in 2022 at ETH Zurich, Transcality is focused on creating innovative tools for modern transportation challenges.

Under Industries is a Swiss deep-tech startup developing autonomous Micro Tunnel Boring Robots (MTBRs) for underground utility installation. Spun out of Swissloop Tunneling at ETH Zürich, the company combines micro-tunnelling with in-situ thermoplastic pipe extrusion, enabling pipe installation without prefabrication or large-scale excavation. The initial target market is power distribution grid undergrounding for Swiss and European distribution system operators.

UNOMR is a TechBio spinout from ETH Zurich pioneering single-molecule protein modification analysis via a serial nanopore sensor, with an initial focus on protein glycosylation. Operating in a US$60B market, their patented platform has broad applications across pharma, healthcare, and food science, delivering unprecedented protein insights for therapeutic discovery and medical food innovation. With a vision of bringing advanced proteomics to the patient, UNOMR aims to accelerate the next leap in precision medicine.

ValTech Lifesciences is a Bern-based medtech spin-off from the ARTORG Center at the University of Bern, developing patented design features for prosthetic heart valve leaflets. Applying biomimetic flow-control geometry from aerospace engineering, its OEM-ready technology reduces thrombogenicity and extends valve durability. The company operates a B2B model, positioning manufacturers as customers and acquirers.

Vamoz AG is a Swiss tech startup that facilitates remote work abroad for employees. The company offers a web-based application where employees can request to work from different locations, and HR can manage these requests by assessing legal and business risks. The solution helps companies maintain oversight of their workforce while offering remote work as a non-monetary benefit to attract and retain talent. Vamoz AG was founded in November 2022 and is headquartered in Zurich.

Verretex SA is a Swiss cleantech startup based at EPFL Innovation Park, pioneering the regeneration of high-performance glass fiber textiles from 100% recycled fiberglass. Spun out of EPFL and INSA de Lyon research, Verretex has developed a proprietary process that restores recycled fibers to virgin-like quality, making them suitable for demanding applications in construction, automotive, marine, energy, and more. By turning composite waste into valuable materials, the company promotes circularity in the composites industry.

viboo AG, founded in March 2022 and headquartered in Dübendorf, Switzerland, offers a cloud platform that connects to IoT devices in light commercial and multi-family buildings to enhance operational efficiency through AI-driven methods, notably Self-Learning Predictive Control. Developed from five years of research at Empa and ETH Zurich, their core algorithm can reduce heating energy consumption by up to 40% compared to industry-standard solutions while improving occupant comfort. The viboo cockpit, a Building Management System (BMS) for operators, provides insights into energy and comfort performance, conducts real-time data-driven system health analyses, and facilitates seamless operation of existing buildings. The team comprises experts in building automation, experienced software engineers, and professionals from the real estate sector.

WasteFlow SA, founded in June 2024 and based in Lausanne, Switzerland, develops AI-powered vision systems to improve recycling processes. By integrating these systems into existing machinery, WasteFlow aims to enhance sorting efficiency and address challenges in recycling operations. Their SaaS platform provides real-time performance insights and machine adjustments to optimize energy use and increase recycling rates. The company was founded by EPFL and ETH Zurich alumni with expertise in computer vision and industrial product development. Their SaaS platform targets a total addressable market of CHF 5 billion, offering real-time key performance indicators and dynamic machine settings to simplify operations, enhance energy efficiency, and increase recycling rates.

WattAnyWhere offers a groundbreaking solution to the lengthy and costly process of connecting to the power grid for outputs of 300kW or more, through its Bioenergy-On-Demand fuel cell system. Developed in partnership with EPFL, HES- SO, and industrial collaborators, this off-grid, pollutant-free system utilizes renewable ethanol—a safe and economical liquid hydrogen carrier—to generate high-power, clean electricity. As the transition from conventional vehicles accelerates, WattAnyWhere's innovative approach repurposes surplus ethanol to support the growth of electric mobility.

YQuantum develops miniaturized cryogenic hardware solutions that tackle one of quantum computing’s central challenges – scalability – by bridging the gap between laboratory prototypes and commercially viable systems through compact, high-performance components that are essential for building scalable quantum computers.